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	<title>Comments on: Drinking at altitude?</title>
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	<link>http://joshandamy.org/blog/2005/10/05/drinking-at-altitude/</link>
	<description>Moving, Marrying, and settling in Colorado</description>
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		<title>By: PP</title>
		<link>http://joshandamy.org/blog/2005/10/05/drinking-at-altitude/comment-page-1/#comment-319</link>
		<dc:creator>PP</dc:creator>
		<pubDate>Wed, 12 Jan 2011 13:03:15 +0000</pubDate>
		<guid isPermaLink="false">http://joshandamy.org/blog/index.php/2005/10/04/drinking-at-altitude/#comment-319</guid>
		<description>My guess would be that the higher altitude does two things. First when travelling into areas with less oxygen available, high altitudes, it could have an impact on the &quot;side effects&quot; of drinking (not directly on liver metabolism... but could eventually indirectly, creating &#039;sensitivities&#039; in some) by reducing Oxidative Stress capacities, part of the condition of uncoordination etc. 

Secondly you would build up &quot;tolerance&quot; to the imbalances coming from high altitudes (like &quot;learning&quot; what it feels like to walk on a moving ship, and the brain/body learning to coordinate under those conditions). So you are better at remaining cooridanted at levels of intoxication that impair others when they are not as &quot;use&quot; to it. 

Many factors come into play for &#039;tolerance&quot; to intoxication. Liver metabolism, oxidation may play a role, but may not play the strongest role, hence very little change in blood levels (indications of liver), but a difference in cognitive performance and &#039;balance&quot; at different altitudes. And frankly when it comes to science studies, since metabolism, while there may be &quot;averages&quot;, can also be immensely personal, and a rethinking of the &quot;dose makes the poison&quot; to both tolerance and poisoning levels will depend on the health of the person, the food eaten, sleep, etc.. a combination of factors, altitude may be just one of several nonlinear factors at play.
http://www.nytimes.com/2008/09/02/health/02real.html?_r=1

(fyi, difference in Holland may take into consideration pasteurization and additives of those beers (many people notice a difference in bottled/microbrew &quot;buzz&quot;. Again some &quot;drunken&quot; symptoms might impact depend on combination of nutritive factors and &quot;side effects&quot;, or other &quot;toxic&quot; substances increasing load and capacity of liver metabolism)

This was an interesting article about O2 infused beverage that got you drunk the same, but sobered up quicker (supposedly b/c the added 02 &quot;aided&quot; the liver, aka the liver didn&#039;t have to work as hard or use up it&#039;s own supply... interesting theory)
http://io9.com/5481058/scientists-have-discovered-booze-that-wont-give-you-a-hangover</description>
		<content:encoded><![CDATA[<p>My guess would be that the higher altitude does two things. First when travelling into areas with less oxygen available, high altitudes, it could have an impact on the &#8220;side effects&#8221; of drinking (not directly on liver metabolism&#8230; but could eventually indirectly, creating &#8216;sensitivities&#8217; in some) by reducing Oxidative Stress capacities, part of the condition of uncoordination etc. </p>
<p>Secondly you would build up &#8220;tolerance&#8221; to the imbalances coming from high altitudes (like &#8220;learning&#8221; what it feels like to walk on a moving ship, and the brain/body learning to coordinate under those conditions). So you are better at remaining cooridanted at levels of intoxication that impair others when they are not as &#8220;use&#8221; to it. </p>
<p>Many factors come into play for &#8216;tolerance&#8221; to intoxication. Liver metabolism, oxidation may play a role, but may not play the strongest role, hence very little change in blood levels (indications of liver), but a difference in cognitive performance and &#8216;balance&#8221; at different altitudes. And frankly when it comes to science studies, since metabolism, while there may be &#8220;averages&#8221;, can also be immensely personal, and a rethinking of the &#8220;dose makes the poison&#8221; to both tolerance and poisoning levels will depend on the health of the person, the food eaten, sleep, etc.. a combination of factors, altitude may be just one of several nonlinear factors at play.<br />
<a href="http://www.nytimes.com/2008/09/02/health/02real.html?_r=1" rel="nofollow">http://www.nytimes.com/2008/09/02/health/02real.html?_r=1</a></p>
<p>(fyi, difference in Holland may take into consideration pasteurization and additives of those beers (many people notice a difference in bottled/microbrew &#8220;buzz&#8221;. Again some &#8220;drunken&#8221; symptoms might impact depend on combination of nutritive factors and &#8220;side effects&#8221;, or other &#8220;toxic&#8221; substances increasing load and capacity of liver metabolism)</p>
<p>This was an interesting article about O2 infused beverage that got you drunk the same, but sobered up quicker (supposedly b/c the added 02 &#8220;aided&#8221; the liver, aka the liver didn&#8217;t have to work as hard or use up it&#8217;s own supply&#8230; interesting theory)<br />
<a href="http://io9.com/5481058/scientists-have-discovered-booze-that-wont-give-you-a-hangover" rel="nofollow">http://io9.com/5481058/scientists-have-discovered-booze-that-wont-give-you-a-hangover</a></p>
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		<title>By: Brandy</title>
		<link>http://joshandamy.org/blog/2005/10/05/drinking-at-altitude/comment-page-1/#comment-303</link>
		<dc:creator>Brandy</dc:creator>
		<pubDate>Fri, 11 Dec 2009 19:00:57 +0000</pubDate>
		<guid isPermaLink="false">http://joshandamy.org/blog/index.php/2005/10/04/drinking-at-altitude/#comment-303</guid>
		<description>Just going by what I&#039;ve read on this page, and my own experience. I don&#039;t live at a high altitude, I&#039;m at about 280 ft below sea level. Since moving here I&#039;ve noticed a difference, I feel more of an effect off of less. I don&#039;t know how the altitude sickness works . . . but I would guess that the effects of altitude would be there whether or not you were drinking. So why would a noticeable change, (feeling tipsy after two glasses of wine, instead of three) be attributed to altitude sickness versus the wine. Is it impossible to think that a change in environment could affect the human body in such a way?
However, some posts say you can drink more than at sea level and others say less. The article itself is misleading in that way.</description>
		<content:encoded><![CDATA[<p>Just going by what I&#8217;ve read on this page, and my own experience. I don&#8217;t live at a high altitude, I&#8217;m at about 280 ft below sea level. Since moving here I&#8217;ve noticed a difference, I feel more of an effect off of less. I don&#8217;t know how the altitude sickness works . . . but I would guess that the effects of altitude would be there whether or not you were drinking. So why would a noticeable change, (feeling tipsy after two glasses of wine, instead of three) be attributed to altitude sickness versus the wine. Is it impossible to think that a change in environment could affect the human body in such a way?<br />
However, some posts say you can drink more than at sea level and others say less. The article itself is misleading in that way.</p>
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		<title>By: Bryan</title>
		<link>http://joshandamy.org/blog/2005/10/05/drinking-at-altitude/comment-page-1/#comment-196</link>
		<dc:creator>Bryan</dc:creator>
		<pubDate>Wed, 14 Jan 2009 03:44:16 +0000</pubDate>
		<guid isPermaLink="false">http://joshandamy.org/blog/index.php/2005/10/04/drinking-at-altitude/#comment-196</guid>
		<description>You are not really &quot;more drunk,&quot; you are simply feeling the effects of the alcohol plus the effects of altitude, which are likely greater than their sums.

http://www.nytimes.com/2008/09/02/health/02real.html</description>
		<content:encoded><![CDATA[<p>You are not really &#8220;more drunk,&#8221; you are simply feeling the effects of the alcohol plus the effects of altitude, which are likely greater than their sums.</p>
<p><a href="http://www.nytimes.com/2008/09/02/health/02real.html" rel="nofollow">http://www.nytimes.com/2008/09/02/health/02real.html</a></p>
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		<title>By: paul</title>
		<link>http://joshandamy.org/blog/2005/10/05/drinking-at-altitude/comment-page-1/#comment-27</link>
		<dc:creator>paul</dc:creator>
		<pubDate>Sun, 25 Nov 2007 06:13:12 +0000</pubDate>
		<guid isPermaLink="false">http://joshandamy.org/blog/index.php/2005/10/04/drinking-at-altitude/#comment-27</guid>
		<description>Hey I agree with the post, I live in washington d.c. And I go to college in new mexico, which is at 5300 feet above sea level. Right now I&#039;m writing this on 16 beers, and I could never handle that many in nm. Its true the altitude makes a huge difference., just try it</description>
		<content:encoded><![CDATA[<p>Hey I agree with the post, I live in washington d.c. And I go to college in new mexico, which is at 5300 feet above sea level. Right now I&#8217;m writing this on 16 beers, and I could never handle that many in nm. Its true the altitude makes a huge difference., just try it</p>
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		<title>By: Craig</title>
		<link>http://joshandamy.org/blog/2005/10/05/drinking-at-altitude/comment-page-1/#comment-26</link>
		<dc:creator>Craig</dc:creator>
		<pubDate>Mon, 17 Sep 2007 20:33:37 +0000</pubDate>
		<guid isPermaLink="false">http://joshandamy.org/blog/index.php/2005/10/04/drinking-at-altitude/#comment-26</guid>
		<description>I just found this discussion by doing a search for &quot;alcohol high altitude.&quot; The reason I did this search is that I live in Colorado at about 6,000 feet and I just went to Holland where I spent a week at sea level. One night we all went out and I had the equivelant of about 10 or 12 beers, and I barely even had a buzz! And we are talking about high powered 9% alcohol Belgian beers. After a while I was just tired and went back to my hotel. This to me, is proof that alcohol has a much lesser effect at sea level. I can guarantee you that I would have been pretty hammered if I would have drank this same amount at home... and all I was was &quot;tired&quot; in Holland.</description>
		<content:encoded><![CDATA[<p>I just found this discussion by doing a search for &#8220;alcohol high altitude.&#8221; The reason I did this search is that I live in Colorado at about 6,000 feet and I just went to Holland where I spent a week at sea level. One night we all went out and I had the equivelant of about 10 or 12 beers, and I barely even had a buzz! And we are talking about high powered 9% alcohol Belgian beers. After a while I was just tired and went back to my hotel. This to me, is proof that alcohol has a much lesser effect at sea level. I can guarantee you that I would have been pretty hammered if I would have drank this same amount at home&#8230; and all I was was &#8220;tired&#8221; in Holland.</p>
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		<title>By: Christopher</title>
		<link>http://joshandamy.org/blog/2005/10/05/drinking-at-altitude/comment-page-1/#comment-25</link>
		<dc:creator>Christopher</dc:creator>
		<pubDate>Fri, 07 Oct 2005 16:36:15 +0000</pubDate>
		<guid isPermaLink="false">http://joshandamy.org/blog/index.php/2005/10/04/drinking-at-altitude/#comment-25</guid>
		<description>Well, while I suppose I should be completely compelled by the anecdotal experiences and a reference to &quot;Modern Drunkard Magazine&quot; the post spurred me to do a little Googling of my own.  (Frankly, I just wasn&#039;t buying into the assertion that the relative partial pressure of O2 in the air would effect the metabolic functioning of the liver enough to have a tangible impact on alcohol intoxication relative to alcohol intake.)  After browsing a few journal articles I&#039;ve come away with the following impressions:

1) From the University of Texas at Austin&#039;s Addiction Science Research &amp; Education Center (http://www.utexas.edu/research/asrec/alcoholfacts.html): &quot;There is no credible research evidence for the following statements about alcohol use: 1) alcohol makes you more intoxicated at high altitudes, compared to sea level, 2) alcohol cures colds and intestinal infections, and 3) alcohol increases digestion of foods. (February 12, 2001)&quot;

2) I also came across information indicating that &quot;Alcohol creates histotoxic hypoxia. For example, an individual who has consumed 1 ounce of alcohol may have a physiological altitude of 2,000 feet.&quot;  So, rather than high altitude making a person more intoxicated it appears that alcohol creates the physiological experience of being at higher altitude.  Perhaps people are confusing &quot;drunkeness&quot; with &quot;altitude sickness&quot;?

3) Perhaps the most compelling anecdote to me is that most of the people I know from high altitudes are WEAK drinkers ;-)</description>
		<content:encoded><![CDATA[<p>Well, while I suppose I should be completely compelled by the anecdotal experiences and a reference to &#8220;Modern Drunkard Magazine&#8221; the post spurred me to do a little Googling of my own.  (Frankly, I just wasn&#8217;t buying into the assertion that the relative partial pressure of O2 in the air would effect the metabolic functioning of the liver enough to have a tangible impact on alcohol intoxication relative to alcohol intake.)  After browsing a few journal articles I&#8217;ve come away with the following impressions:</p>
<p>1) From the University of Texas at Austin&#8217;s Addiction Science Research &amp; Education Center (<a href="http://www.utexas.edu/research/asrec/alcoholfacts.html" rel="nofollow">http://www.utexas.edu/research/asrec/alcoholfacts.html</a>): &#8220;There is no credible research evidence for the following statements about alcohol use: 1) alcohol makes you more intoxicated at high altitudes, compared to sea level, 2) alcohol cures colds and intestinal infections, and 3) alcohol increases digestion of foods. (February 12, 2001)&#8221;</p>
<p>2) I also came across information indicating that &#8220;Alcohol creates histotoxic hypoxia. For example, an individual who has consumed 1 ounce of alcohol may have a physiological altitude of 2,000 feet.&#8221;  So, rather than high altitude making a person more intoxicated it appears that alcohol creates the physiological experience of being at higher altitude.  Perhaps people are confusing &#8220;drunkeness&#8221; with &#8220;altitude sickness&#8221;?</p>
<p>3) Perhaps the most compelling anecdote to me is that most of the people I know from high altitudes are WEAK drinkers <img src='http://joshandamy.org/blog/wp-includes/images/smilies/icon_wink.gif' alt=';-)' class='wp-smiley' /> </p>
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